Depending on the Chassis you are putting the ASI cards in, there may need to be an adjustment to the J9 Jumper on 6000 series cards. J9, by default is "unjumpered". This means it's expecting a 2.1 compliant PCI bus with ATX power supply. If that is not the case, then you would need to jumper J9 to make it AT compliant. It should be noted that Audio Science is not compliant with Mako 233Mhz Motherboards and will not work properly.